Nifuroxazide inhibits survival of multiple myeloma cells by directly inhibiting STAT3

Constitutive activation of the transcription factor STAT3 contributes to the pathogenesis of many cancers, including multiple myeloma (MM). Since STAT3 is dispensable in most normal tissue, targeted inhibition of STAT3 is an attractive therapy for patients with these cancers. To identify STAT3 inhib...

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Detalhes bibliográficos
Main Authors: Nelson, Erik A., Walker, Sarah R., Kepich, Alicia, Gashin, Laurie B., Hideshima, Teru, Ikeda, Hiroshi, Chauhan, Dharminder, Anderson, Kenneth C., Frank, David A.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society of Hematology 2008
Assuntos:
Neoplasia
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2597607/
https://ncbi.nlm.nih.gov/pubmed/18824601
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1182/blood-2007-12-129718
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