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A dual PI3K α/mTOR inhibitor cooperates with blockade of EGFR in PTEN-mutant glioma
We have shown previously that blockade of EGFR cooperates with a pan-selective inhibitor of PI3K in EGFR-driven glioma. In this communication, we tested EGFR-driven glioma differing in PTEN-status, treating with the EGFR inhibitor erlotinib and a novel dual inhibitor of PI3Kα and mTOR (PI-103). Erlo...
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| Main Authors: | , , , , , |
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| Format: | Artigo |
| Language: | Inglês |
| Published: |
2007
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| Subjects: | |
| Online Access: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2597547/ https://ncbi.nlm.nih.gov/pubmed/17804702 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1158/0008-5472.CAN-07-2154 |
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