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Coordinated control of connexin 26 and connexin 30 at the regulatory and functional level in the inner ear

Connexin 26 (Cx26) and connexin 30 (Cx30) are encoded by two genes (GJB2 and GJB6, respectively) that are found within 50 kb in the same complex deafness locus, DFNB1. Immunocytochemistry and quantitative PCR analysis of Cx30 KO mouse cultures revealed that Cx26 is downregulated at the protein level...

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Detalhes bibliográficos
Main Authors: Ortolano, Saida, Di Pasquale, Giovanni, Crispino, Giulia, Anselmi, Fabio, Mammano, Fabio, Chiorini, John A.
Formato: Artigo
Idioma:Inglês
Publicado em: National Academy of Sciences 2008
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2596232/
https://ncbi.nlm.nih.gov/pubmed/19047647
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0800831105
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