ATP release through connexin hemichannels and gap junction transfer of second messengers propagate Ca(2+) signals across the inner ear

Extracellular ATP controls various signaling systems including propagation of intercellular Ca(2+) signals (ICS). Connexin hemichannels, P2x7 receptors (P2x7Rs), pannexin channels, anion channels, vesicles, and transporters are putative conduits for ATP release, but their involvement in ICS remains...

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Bibliographische Detailangaben
Hauptverfasser: Anselmi, Fabio, Hernandez, Victor H., Crispino, Giulia, Seydel, Anke, Ortolano, Saida, Roper, Stephen D., Kessaris, Nicoletta, Richardson, William, Rickheit, Gesa, Filippov, Mikhail A., Monyer, Hannah, Mammano, Fabio
Format: Artigo
Sprache:Inglês
Veröffentlicht: National Academy of Sciences 2008
Schlagworte:
Biological Sciences
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC2596208/
https://ncbi.nlm.nih.gov/pubmed/19047635
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0800793105
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