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In vivo genetic manipulation of inner ear connexin expression by bovine adeno-associated viral vectors

We have previously shown that in vitro transduction with bovine adeno–associated viral (BAAV) vectors restores connexin expression and rescues gap junction coupling in cochlear organotypic cultures from connexin–deficient mice that are models DFNB1 nonsyndromic hearing loss and deafness. The aims of...

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Bibliografiske detaljer
Udgivet i:Sci Rep
Main Authors: Crispino, Giulia, Galindo Ramirez, Fabian, Campioni, Matteo, Zorzi, Veronica, Praetorius, Mark, Di Pasquale, Giovanni, Chiorini, John A., Mammano, Fabio
Format: Artigo
Sprog:Inglês
Udgivet: Nature Publishing Group UK 2017
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5544751/
https://ncbi.nlm.nih.gov/pubmed/28779115
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-017-06759-y
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