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Crystal structure of KPC-2: insights into carbapenemase activity in Class A β-lactamases
β-lactamases inactivate β-lactam antibiotics and are a major cause of antibiotic resistance. The recent outbreaks of Klebsiella pneumoniae carbapenem-resistant (KPC) infections mediated by KPC type β-lactamases are creating a serious threat to our “last resort” antibiotics, the carbapenems. KPC β-la...
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| Hauptverfasser: | , , , , |
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| Format: | Artigo |
| Sprache: | Inglês |
| Veröffentlicht: |
2007
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| Schlagworte: | |
| Online Zugang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2596071/ https://ncbi.nlm.nih.gov/pubmed/17441734 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/bi700300u |
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