The Effect of the Inhibitor–Resistant M69V Substitution on the Structures and Populations of Trans–Enamine β-Lactamase Intermediates

समान संसाधन

• Rational design of a β-lactamase inhibitor achieved via stabilization of the trans-enamine intermediate: 1.28 Å crystal structure of wt SHV-1 complex with a penam sulfone
  द्वारा: Padayatti, Pius S., और अन्य
  प्रकाशित: (2006)
• The importance of the trans-enamine intermediate as a β-lactamase inhibition strategy probed in inhibitor-resistant SHV β-lactamase variants
  द्वारा: Ke, Wei, और अन्य
  प्रकाशित: (2012)
• Sulbactam Forms Only Minimal Amounts of Irreversible Acrylate-Enzyme With SHV-1 β-Lactamase
  द्वारा: Totir, Monica A., और अन्य
  प्रकाशित: (2007)
• Exploring Additional Dimensions of Complexity in Inhibitor Design for Serine β-Lactamases: Mechanistic and Intra- and Inter-molecular Chemistry Approaches
  द्वारा: van den Akker, Focco, और अन्य
  प्रकाशित: (2018)
• Structures of SHV-1 β-Lactamase with Penem and Penam Sulfone Inhibitors That Form Cyclic Intermediates Stabilized by Carbonyl Conjugation
  द्वारा: Ke, Wei, और अन्य
  प्रकाशित: (2012)