Transcriptional enhancement by GATA1-occupied DNA segments is strongly associated with evolutionary constraint on the binding site motif

Tissue development and function are exquisitely dependent on proper regulation of gene expression, but it remains controversial whether the genomic signals controlling this process are subject to strong selective constraint. While some studies show that highly constrained noncoding regions act to en...

Celý popis

Uloženo v:
Podrobná bibliografie
Hlavní autoři: Cheng, Yong, King, David C., Dore, Louis C., Zhang, Xinmin, Zhou, Yuepin, Zhang, Ying, Dorman, Christine, Abebe, Demesew, Kumar, Swathi A., Chiaromonte, Francesca, Miller, Webb, Green, Roland D., Weiss, Mitchell J., Hardison, Ross C.
Médium: Artigo
Jazyk:Inglês
Vydáno: Cold Spring Harbor Laboratory Press 2008
Témata:
Letter
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC2593580/
https://ncbi.nlm.nih.gov/pubmed/18818370
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1101/gr.083089.108
Tagy: Přidat tag
Žádné tagy, Buďte první, kdo otaguje tento záznam!

Podobné jednotky