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Noncoding regulatory sequences of Ciona exhibit strong correspondence between evolutionary constraint and functional importance

We show that sequence comparisons at different levels of resolution can efficiently guide functional analyses of regulatory regions in the ascidians Ciona savignyi and Ciona intestinalis. Sequence alignments of several tissue-specific genes guided discovery of minimal regulatory regions that are act...

Deskribapen osoa

Gorde:
Xehetasun bibliografikoak
Egile Nagusiak: Johnson, David S., Davidson, Brad, Brown, Christopher D., Smith, William C., Sidow, Arend
Formatua: Artigo
Hizkuntza:Inglês
Argitaratua: Cold Spring Harbor Laboratory Press 2004
Gaiak:
Sarrera elektronikoa:https://ncbi.nlm.nih.gov/pmc/articles/PMC534669/
https://ncbi.nlm.nih.gov/pubmed/15545496
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1101/gr.2964504
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