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Noncoding regulatory sequences of Ciona exhibit strong correspondence between evolutionary constraint and functional importance
We show that sequence comparisons at different levels of resolution can efficiently guide functional analyses of regulatory regions in the ascidians Ciona savignyi and Ciona intestinalis. Sequence alignments of several tissue-specific genes guided discovery of minimal regulatory regions that are act...
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| Main Authors: | , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Cold Spring Harbor Laboratory Press
2004
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC534669/ https://ncbi.nlm.nih.gov/pubmed/15545496 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1101/gr.2964504 |
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