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Evaluation of a focused library of N-aryl L-homoserine lactones reveals a new set of potent quorum sensing modulators

A focused library of N-aryl l-homoserine lactones was designed around known lactone leads and evaluated for antagonistic and agonistic activity against quorum-sensing receptors in Agrobacterium tumefaciens, Pseudomonas aeruginosa, and Vibrio fischeri. Several compounds were identified with significa...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Hauptverfasser: Geske, Grant D., Mattmann, Margrith E., Blackwell, Helen E.
Format: Artigo
Sprache:Inglês
Veröffentlicht: 2008
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC2593151/
https://ncbi.nlm.nih.gov/pubmed/18760602
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bmcl.2008.07.089
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