Impact of Secondary Structure of Toll-Like Receptor 9 Agonists on Interferon Alpha Induction

Oligodeoxynucleotides containing a CpG motif and double- or multistranded structure-forming sequences act as agonists of Toll-like receptor 9 (TLR9) and induce high levels of interferon alpha (IFN-α) in addition to other Th1-type cytokines. In the present study, we evaluated three highly effective I...

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Hlavní autoři: Yu, Dong, Putta, Mallikarjuna R., Bhagat, Lakshmi, Dai, Meiru, Wang, Daqing, Trombino, Anthony F., Sullivan, Tim, Kandimalla, Ekambar R., Agrawal, Sudhir
Médium: Artigo
Jazyk:Inglês
Vydáno: American Society for Microbiology (ASM) 2008
Témata:
Antiviral Agents
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC2592873/
https://ncbi.nlm.nih.gov/pubmed/18852281
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/AAC.00701-08
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