Stabilized immune modulatory RNA compounds as agonists of Toll-like receptors 7 and 8

Viral and synthetic single-stranded RNAs are the ligands for Toll-like receptor (TLR)7 and TLR8. However, single-stranded RNA is rapidly degraded by ubiquitous RNases, and the studies reported to date have used RNA with lipid carriers. To overcome nuclease susceptibility of RNA, we have synthesized...

Fuld beskrivelse

Na minha lista:
Bibliografiske detaljer
Main Authors: Lan, Tao, Kandimalla, Ekambar R., Yu, Dong, Bhagat, Lakshmi, Li, Yukui, Wang, Daqing, Zhu, FuGang, Tang, Jimmy X., Putta, Mallikarjuna R., Cong, YanPing, Trombino, Anthony F., Sullivan, Tim, Agrawal, Sudhir
Format: Artigo
Sprog:Inglês
Udgivet: National Academy of Sciences 2007
Fag:
Biological Sciences
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC1959454/
https://ncbi.nlm.nih.gov/pubmed/17698957
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0706059104
Tags: Tilføj Tag
Ingen Tags, Vær først til at tagge denne postø!

Lignende værker