Novel oligodeoxynucleotide agonists of TLR9 containing N(3)-Me-dC or N(1)-Me-dG modifications

Synthetic oligodeoxynucleotides containing unmethylated CpG motifs activate Toll-Like Receptor 9 (TLR9). Our previous studies have shown the role of hydrogen-bond donor and acceptor groups of cytosine and guanine in the CpG motif and identified synthetic immunostimulatory motifs. In the present stud...

Ausführliche Beschreibung

Gespeichert in:
Bibliographische Detailangaben
Hauptverfasser: Putta, Mallikarjuna Reddy, Zhu, FuGang, Li, Yukui, Bhagat, Lakshmi, Cong, YanPing, Kandimalla, Ekambar R., Agrawal, Sudhir
Format: Artigo
Sprache:Inglês
Veröffentlicht: Oxford University Press 2006
Schlagworte:
Article
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC1904100/
https://ncbi.nlm.nih.gov/pubmed/16798912
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/nar/gkl430
Tags: Tag hinzufügen
Keine Tags, Fügen Sie den ersten Tag hinzu!

Ähnliche Einträge