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The Hsk1(Cdc7) Replication Kinase Regulates Origin Efficiency

Origins of DNA replication are generally inefficient, with most firing in fewer than half of cell cycles. However, neither the mechanism nor the importance of the regulation of origin efficiency is clear. In fission yeast, origin firing is stochastic, leading us to hypothesize that origin inefficien...

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Bibliographic Details
Main Authors: Patel, Prasanta K., Kommajosyula, Naveen, Rosebrock, Adam, Bensimon, Aaron, Leatherwood, Janet, Bechhoefer, John, Rhind, Nicholas
Format: Artigo
Language:Inglês
Published: The American Society for Cell Biology 2008
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Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC2592646/
https://ncbi.nlm.nih.gov/pubmed/18799612
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1091/mbc.E08-06-0645
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