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Cdc2 tyrosine phosphorylation is not required for the S-phase DNA damage checkpoint in fission yeast

The S-phase DNA damage checkpoint slows replication when damage occurs during S phase. Cdc25, which activates Cdc2 by dephosphorylating tyrosine-15, has been shown to be a downstream target of the checkpoint in metazoans, but its role is not clear in fission yeast. The dephosphorylation of Cdc2 has...

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Bibliografische gegevens
Hoofdauteurs: Kommajosyula, Naveen, Rhind, Nicholas
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: 2006
Onderwerpen:
Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC2562503/
https://ncbi.nlm.nih.gov/pubmed/17102632
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