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Tyrosine Phosphorylation of Cdc2 Is Required for the Replication Checkpoint in Schizosaccharomyces pombe

The DNA replication checkpoint inhibits mitosis in cells that are unable to replicate their DNA, as when nucleotide biosynthesis is inhibited by hydroxyurea. In the fission yeast Schizosaccharomyces pombe, genetic evidence suggests that this checkpoint involves the inhibition of Cdc2 activity throug...

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Detalles Bibliográficos
Main Authors: Rhind, Nicholas, Russell, Paul
Formato: Artigo
Idioma:Inglês
Publicado: American Society for Microbiology 1998
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Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC108961/
https://ncbi.nlm.nih.gov/pubmed/9632761
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