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Tyrosine Phosphorylation of Cdc2 Is Required for the Replication Checkpoint in Schizosaccharomyces pombe

The DNA replication checkpoint inhibits mitosis in cells that are unable to replicate their DNA, as when nucleotide biosynthesis is inhibited by hydroxyurea. In the fission yeast Schizosaccharomyces pombe, genetic evidence suggests that this checkpoint involves the inhibition of Cdc2 activity throug...

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Bibliographic Details
Published in:Mol Cell Biol
Main Authors: Rhind, Nicholas, Russell, Paul
Format: Artigo
Language:Inglês
Published: Taylor & Francis 1998
Subjects:
Online Access:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC108961/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/9632761/
https://ncbi.nlm.nih.govhttps://doi.org/10.1128/mcb.18.7.3782
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