The Fission Yeast Rad32 (Mre11)-Rad50-Nbs1 Complex Is Required for the S-Phase DNA Damage Checkpoint

Mre11, Rad50, and Nbs1 form a conserved heterotrimeric complex that is involved in recombination and DNA damage checkpoints. Mutations in this complex disrupt the S-phase DNA damage checkpoint, the checkpoint which slows replication in response to DNA damage, and cause chromosome instability and can...

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Detalhes bibliográficos
Main Authors: Chahwan, Charly, Nakamura, Toru M., Sivakumar, Sasirekha, Russell, Paul, Rhind, Nicholas
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology 2003
Assuntos:
DNA Dynamics and Chromosome Structure
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC193710/
https://ncbi.nlm.nih.gov/pubmed/12944482
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/MCB.23.18.6564-6573.2003
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