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Reconciling stochastic origin firing with defined replication timing

Eukaryotic chromosomes replicate with defined timing patterns. However, the mechanism that regulates the timing of replication is unknown. In particular, there is an apparent conflict between population experiments, which show defined average replication times, and single-molecule experiments, which...

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Detalhes bibliográficos
Main Authors: Rhind, Nicholas, Yang, Scott Cheng-Hsin, Bechhoefer, John
Formato: Artigo
Idioma:Inglês
Publicado em: 2010
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2862975/
https://ncbi.nlm.nih.gov/pubmed/20205352
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