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Reconciling stochastic origin firing with defined replication timing

Eukaryotic chromosomes replicate with defined timing patterns. However, the mechanism that regulates the timing of replication is unknown. In particular, there is an apparent conflict between population experiments, which show defined average replication times, and single-molecule experiments, which...

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Autors principals: Rhind, Nicholas, Yang, Scott Cheng-Hsin, Bechhoefer, John
Format: Artigo
Idioma:Inglês
Publicat: 2010
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC2862975/
https://ncbi.nlm.nih.gov/pubmed/20205352
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