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Modeling genome-wide replication kinetics reveals a mechanism for regulation of replication timing

Microarrays are powerful tools to probe genome-wide replication kinetics. The rich data sets that result contain more information than has been extracted by current methods of analysis. In this paper, we present an analytical model that incorporates probabilistic initiation of origins and passive re...

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Detalhes bibliográficos
Main Authors: Yang, Scott Cheng-Hsin, Rhind, Nicholas, Bechhoefer, John
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group 2010
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2950085/
https://ncbi.nlm.nih.gov/pubmed/20739926
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/msb.2010.61
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