Replication timing is regulated by the number of MCMs loaded at origins

Replication timing is a crucial aspect of genome regulation that is strongly correlated with chromatin structure, gene expression, DNA repair, and genome evolution. Replication timing is determined by the timing of replication origin firing, which involves activation of MCM helicase complexes loaded...

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Detalhes bibliográficos
Publicado no:Genome Res
Main Authors: Das, Shankar P., Borrman, Tyler, Liu, Victor W.T., Yang, Scott C.-H., Bechhoefer, John, Rhind, Nicholas
Formato: Artigo
Idioma:Inglês
Publicado em: Cold Spring Harbor Laboratory Press 2015
Assuntos:
Research
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4665009/
https://ncbi.nlm.nih.gov/pubmed/26359232
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1101/gr.195305.115
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