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The capacity of origins to load MCM establishes replication timing patterns

Loading of the MCM replicative helicase at origins of replication is a highly regulated process that precedes DNA replication in all eukaryotes. The stoichiometry of MCM loaded at origins has been proposed to be a key determinant of when those origins initiate replication during S phase. Nevertheles...

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Bibliografiset tiedot
Julkaisussa:PLoS Genet
Päätekijät: Dukaj, Livio, Rhind, Nicholas
Aineistotyyppi: Artigo
Kieli:Inglês
Julkaistu: Public Library of Science 2021
Aiheet:
Linkit:https://ncbi.nlm.nih.gov/pmc/articles/PMC8023499/
https://ncbi.nlm.nih.gov/pubmed/33764973
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pgen.1009467
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