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The Hsk1(Cdc7) Replication Kinase Regulates Origin Efficiency

Origins of DNA replication are generally inefficient, with most firing in fewer than half of cell cycles. However, neither the mechanism nor the importance of the regulation of origin efficiency is clear. In fission yeast, origin firing is stochastic, leading us to hypothesize that origin inefficien...

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Detalhes bibliográficos
Main Authors: Patel, Prasanta K., Kommajosyula, Naveen, Rosebrock, Adam, Bensimon, Aaron, Leatherwood, Janet, Bechhoefer, John, Rhind, Nicholas
Formato: Artigo
Idioma:Inglês
Publicado em: The American Society for Cell Biology 2008
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2592646/
https://ncbi.nlm.nih.gov/pubmed/18799612
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1091/mbc.E08-06-0645
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