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The kappa-opioid agonist U69,593 blocks cocaine-induced enhancement of brain stimulation reward
BACKGROUND: Increasing evidence indicates that brain kappa-opioid receptors (KORs) are involved in regulation of mood states. In animal models often used to study psychiatric illness, KOR agonists produce depressive-like effects (e.g., anhedonia) whereas KOR antagonists produce antidepressant- and a...
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| Main Authors: | , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2008
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2592608/ https://ncbi.nlm.nih.gov/pubmed/18639235 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.biopsych.2008.05.029 |
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