ΔFosB enhances the rewarding effects of cocaine while reducing the pro-depressive effects of the kappa-opioid agonist U50488

BACKGROUND: Elevated expression of the transcription factor ΔFosB accompanies repeated exposure to drugs of abuse, particularly in brain areas associated with reward and motivation (e.g., nucleus accumbens [NAc]). The persistent effects of ΔFosB on target genes may play an important role in the deve...

Descrición completa

Gardado en:
Detalles Bibliográficos
Main Authors: Muschamp, John W., Nemeth, Christina L., Robison, Alfred J., Nestler, Eric J., Carlezon, William A.
Formato: Artigo
Idioma:Inglês
Publicado: 2011
Assuntos:
Article
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC3230776/
https://ncbi.nlm.nih.gov/pubmed/21962331
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.biopsych.2011.08.011
Tags: Engadir etiqueta
Sen Etiquetas, Sexa o primeiro en etiquetar este rexistro!

Títulos similares