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Effects of striatal ΔFosB overexpression and ketamine on social defeat stress-induced anhedonia in mice

BACKGROUND: Chronic social defeat stress (CSDS) produces persistent behavioral adaptations in mice. In many behavioral assays, it can be difficult to determine if these adaptations reflect core signs of depression. We designed studies to characterize the effects of CSDS on sensitivity to reward, sin...

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Detalhes bibliográficos
Main Authors: Donahue, Rachel J., Muschamp, John W., Russo, Scott J., Nestler, Eric J., Carlezon, William A.
Formato: Artigo
Idioma:Inglês
Publicado em: 2014
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4087093/
https://ncbi.nlm.nih.gov/pubmed/24495460
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.biopsych.2013.12.014
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