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Transcriptional mechanisms of addiction: role of ΔFosB

Regulation of gene expression is considered a plausible mechanism of drug addiction, given the stability of behavioural abnormalities that define an addicted state. Among many transcription factors known to influence the addiction process, one of the best characterized is ΔFosB, which is induced in...

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Bibliographic Details
Main Author: Nestler, Eric J
Format: Artigo
Language:Inglês
Published: The Royal Society 2008
Subjects:
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC2607320/
https://ncbi.nlm.nih.gov/pubmed/18640924
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1098/rstb.2008.0067
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