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Threonine 149 Phosphorylation Enhances ΔFosB Transcriptional Activity to Control Psychomotor Responses to Cocaine

Stable changes in neuronal gene expression have been studied as mediators of addicted states. Of particular interest is the transcription factor ΔFosB, a truncated and stable FosB gene product whose expression in nucleus accumbens (NAc), a key reward region, is induced by chronic exposure to virtual...

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Bibliografski detalji
Glavni autori: Cates, Hannah M., Thibault, Mackenzie, Pfau, Madeline, Heller, Elizabeth, Eagle, Andrew, Gajewski, Paula, Bagot, Rosemary, Colangelo, Christopher, Abbott, Thomas, Rudenko, Gabby, Neve, Rachael, Nestler, Eric J., Robison, Alfred J.
Format: Artigo
Jezik:Inglês
Izdano: Society for Neuroscience 2014
Teme:
Online pristup:https://ncbi.nlm.nih.gov/pmc/articles/PMC4138349/
https://ncbi.nlm.nih.gov/pubmed/25143625
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1523/JNEUROSCI.1611-14.2014
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