Threonine 149 Phosphorylation Enhances ΔFosB Transcriptional Activity to Control Psychomotor Responses to Cocaine

Stable changes in neuronal gene expression have been studied as mediators of addicted states. Of particular interest is the transcription factor ΔFosB, a truncated and stable FosB gene product whose expression in nucleus accumbens (NAc), a key reward region, is induced by chronic exposure to virtual...

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Hlavní autoři: Cates, Hannah M., Thibault, Mackenzie, Pfau, Madeline, Heller, Elizabeth, Eagle, Andrew, Gajewski, Paula, Bagot, Rosemary, Colangelo, Christopher, Abbott, Thomas, Rudenko, Gabby, Neve, Rachael, Nestler, Eric J., Robison, Alfred J.
Médium: Artigo
Jazyk:Inglês
Vydáno: Society for Neuroscience 2014
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On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC4138349/
https://ncbi.nlm.nih.gov/pubmed/25143625
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1523/JNEUROSCI.1611-14.2014
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