Threonine 149 Phosphorylation Enhances ΔFosB Transcriptional Activity to Control Psychomotor Responses to Cocaine

Stable changes in neuronal gene expression have been studied as mediators of addicted states. Of particular interest is the transcription factor ΔFosB, a truncated and stable FosB gene product whose expression in nucleus accumbens (NAc), a key reward region, is induced by chronic exposure to virtual...

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Hauptverfasser: Cates, Hannah M., Thibault, Mackenzie, Pfau, Madeline, Heller, Elizabeth, Eagle, Andrew, Gajewski, Paula, Bagot, Rosemary, Colangelo, Christopher, Abbott, Thomas, Rudenko, Gabby, Neve, Rachael, Nestler, Eric J., Robison, Alfred J.
Format: Artigo
Sprache:Inglês
Veröffentlicht: Society for Neuroscience 2014
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Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4138349/
https://ncbi.nlm.nih.gov/pubmed/25143625
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1523/JNEUROSCI.1611-14.2014
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