In vivo selection of MGMT(P140K) lentivirus–transduced human NOD/SCID repopulating cells without pretransplant irradiation conditioning

Infusion of transduced hematopoietic stem cells into nonmyeloablated hosts results in ineffective in vivo levels of transduced cells. To increase the proportion of transduced cells in vivo, selection based on P140K O(6)-methylguanine-DNA-methyltransferase (MGMT[P140K]) gene transduction and O(6)-ben...

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Detaylı Bibliyografya
Yayımlandı:J Clin Invest
Asıl Yazarlar: Zielske, Steven P., Reese, Jane S., Lingas, Karen T., Donze, Jon R., Gerson, Stanton L.
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: American Society for Clinical Investigation 2003
Konular:
Article
Online Erişim:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC259124/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/14617757/
https://ncbi.nlm.nih.govhttps://doi.org/10.1172/JCI17922
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