Transduction of human NOD/SCID-repopulating cells with both lymphoid and myeloid potential by foamy virus vectors

The efficiency of gene transfer into human hematopoietic stem cells by oncoretroviral vectors is too low for effective gene therapy of most hematologic diseases. Retroviral vectors based on the nonpathogenic foamy viruses (FV) are an alternative gene-transfer system. In this study, human umbilical c...

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Hlavní autoři: Josephson, Neil C., Vassilopoulos, George, Trobridge, Grant D., Priestley, Greg V., Wood, Brent L., Papayannopoulou, Thalia, Russell, David W.
Médium: Artigo
Jazyk:Inglês
Vydáno: The National Academy of Sciences 2002
Témata:
Biological Sciences
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC123061/
https://ncbi.nlm.nih.gov/pubmed/12060773
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.122131099
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