Transduction of human NOD/SCID-repopulating cells with both lymphoid and myeloid potential by foamy virus vectors

The efficiency of gene transfer into human hematopoietic stem cells by oncoretroviral vectors is too low for effective gene therapy of most hematologic diseases. Retroviral vectors based on the nonpathogenic foamy viruses (FV) are an alternative gene-transfer system. In this study, human umbilical c...

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Detalles Bibliográficos
Main Authors: Josephson, Neil C., Vassilopoulos, George, Trobridge, Grant D., Priestley, Greg V., Wood, Brent L., Papayannopoulou, Thalia, Russell, David W.
Formato: Artigo
Idioma:Inglês
Publicado: The National Academy of Sciences 2002
Assuntos:
Biological Sciences
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC123061/
https://ncbi.nlm.nih.gov/pubmed/12060773
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.122131099
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