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Delayed Chain Termination Protects the Anti-hepatitis B Virus Drug Entecavir from Excision by HIV-1 Reverse Transcriptase

Entecavir (ETV) is a potent antiviral nucleoside analogue that is used to treat hepatitis B virus (HBV) infection. Recent clinical studies have demonstrated that ETV is also active against the human immunodeficiency virus type 1 (HIV-1). Unlike all approved nucleoside analogue reverse transcriptase...

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Hlavní autoři: Tchesnokov, Egor P., Obikhod, Aleksandr, Schinazi, Raymond F., Götte, Matthias
Médium: Artigo
Jazyk:Inglês
Vydáno: American Society for Biochemistry and Molecular Biology 2008
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC2590697/
https://ncbi.nlm.nih.gov/pubmed/18940786
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M806797200
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