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Metabolism of melatonin by cytochrome P-450s in rat liver mitochondria and microsomes

In the present study we provide direct evidence for the involvement of rat microsomal cytochrome P450s in melatonin O-demethylation and hydroxylation at two different positions: 2 and 6, as well as generation of N(1)-acetyl-N(2)-formyl-5-methoxy-kynuramine (AFMK) and two unknown products. Moreover,...

Deskribapen osoa

Gorde:
Xehetasun bibliografikoak
Egile Nagusiak: Semak, Igor, Korik, Elena, Antonova, Maria, Wortsman, Jacobo, Slominski, Andrzej
Formatua: Artigo
Hizkuntza:Inglês
Argitaratua: 2008
Gaiak:
Sarrera elektronikoa:https://ncbi.nlm.nih.gov/pmc/articles/PMC2587488/
https://ncbi.nlm.nih.gov/pubmed/18717775
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/j.1600-079X.2008.00630.x
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