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Liver microsomal cytochrome P-450 and the oxidative metabolism of arachidonic acid.

Arachidonic acid is oxidatively metabolized by rat liver microsomes at a rate of approximately 5 nmol per min per mg of protein at 25 degrees C. This reaction is dependent on the presence of NADPH and oxygen. Studies with various inhibitors indicate a role for membrane-bound cytochrome P-450 in the...

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Detalhes bibliográficos
Main Authors: Capdevila, J, Chacos, N, Werringloer, J, Prough, R A, Estabrook, R W
Formato: Artigo
Idioma:Inglês
Publicado em: 1981
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC348745/
https://ncbi.nlm.nih.gov/pubmed/6795631
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