Liver microsomal cytochrome P-450 and the oxidative metabolism of arachidonic acid.

Arachidonic acid is oxidatively metabolized by rat liver microsomes at a rate of approximately 5 nmol per min per mg of protein at 25 degrees C. This reaction is dependent on the presence of NADPH and oxygen. Studies with various inhibitors indicate a role for membrane-bound cytochrome P-450 in the...

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Publicado en:	Proc Natl Acad Sci U S A
Autores principales:	Capdevila, J, Chacos, N, Werringloer, J, Prough, R A, Estabrook, R W
Formato:	Artigo
Lenguaje:	Inglês
Publicado:	National Academy of Sciences 1981
Materias:	Research Article
Acceso en línea:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC348745/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/6795631/ https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.78.9.5362
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