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Liver microsomal cytochrome P-450 and the oxidative metabolism of arachidonic acid.
Arachidonic acid is oxidatively metabolized by rat liver microsomes at a rate of approximately 5 nmol per min per mg of protein at 25 degrees C. This reaction is dependent on the presence of NADPH and oxygen. Studies with various inhibitors indicate a role for membrane-bound cytochrome P-450 in the...
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| Udgivet i: | Proc Natl Acad Sci U S A |
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| Main Authors: | , , , , |
| Format: | Artigo |
| Sprog: | Inglês |
| Udgivet: |
National Academy of Sciences
1981
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| Fag: | |
| Online adgang: | https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC348745/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/6795631/ https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.78.9.5362 |
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