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The cytochrome P450scc system opens an alternate pathway of vitamin D3 metabolism
We show that cytochrome P450scc (CYP11A1) in either a reconstituted system or in isolated adrenal mitochondria can metabolize vitamin D3. The major products of the reaction with reconstituted enzyme were 20-hydroxycholecalciferol and 20,22-dihydroxycholecalciferol, with yields of 16 and 4%, respecti...
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| Hoofdauteurs: | , , , , , , |
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| Formaat: | Artigo |
| Taal: | Inglês |
| Gepubliceerd in: |
2005
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| Onderwerpen: | |
| Online toegang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2234577/ https://ncbi.nlm.nih.gov/pubmed/16098191 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/j.1742-4658.2005.04819.x |
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