Activating mutations in ALK provide a therapeutic target in neuroblastoma

Neuroblastoma, an embryonal tumor of the peripheral sympathetic nervous system, accounts for approximately 15% of all deaths due to childhood cancer1. High-risk neuroblastomas, prevalent in the majority of patients, are rapidly progressive; even with intensive myeloablative chemotherapy, relapse is...

Disgrifiad llawn

Wedi'i Gadw mewn:
Manylion Llyfryddiaeth
Prif Awduron: George, Rani E., Sanda, Takaomi, Hanna, Megan, Fröhling, Stefan, Luther, William, Zhang, Jianming, Ahn, Yebin, Zhou, Wenjun, London, Wendy B., McGrady, Patrick, Xue, Liquan, Zozulya, Sergey, Gregor, Vlad, Webb, Thomas R., Gray, Nathanael S., Gilliland, D. Gary, Diller, Lisa, Greulich, Heidi, Morris, Stephan W., Meyerson, Matthew, Look, A. Thomas
Fformat: Artigo
Iaith:Inglês
Cyhoeddwyd: 2008
Pynciau:
Article
Mynediad Ar-lein:https://ncbi.nlm.nih.gov/pmc/articles/PMC2587486/
https://ncbi.nlm.nih.gov/pubmed/18923525
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/nature07397
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