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Amino acids activate mTOR Complex1 via Ca(2+)/CaM signaling to hVps34
Excess levels of circulating amino acids (AAs) play a causal role in specific human pathologies, including obesity and type 2 diabetes. Moreover, obesity and diabetes are contributing factors in the development of cancer, with recent studies suggesting this link is in part mediated by AA activation...
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| Autores principales: | , , , , , , , , |
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| Formato: | Artigo |
| Lenguaje: | Inglês |
| Publicado: |
2008
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| Materias: | |
| Acceso en línea: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2587347/ https://ncbi.nlm.nih.gov/pubmed/18460336 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.cmet.2008.03.002 |
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