Evaluation in Monkey of [(11)C]PipISB and [(18)F]PipISB as Candidate Radioligands for Imaging Brain Cannabinoid Type-1 (CB(1)) Receptors In Vivo

N-(4-Fluorobenzyl)-4-[3-(piperidin-1-yl)indole-1-sulfonyl]benzamide] (PipISB, 3) is a selective and high potency cannabinoid subtype-1 (CB(1)) receptor inverse agonist. We have previously reported radiosyntheses of [(11)C]3 and [(18)F]3. Here we aimed to evaluate the uptake and CB(1) receptor-specif...

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Main Authors: FINNEMA, SJOERD J., DONOHUE, SEAN R., ZOGHBI, SAMI S., BROWN, AMIRA K., GULYÁS, BALÁZS, INNIS, ROBERT B., HALLDIN, CHRISTER, PIKE, VICTOR W.
Formato: Artigo
Idioma:Inglês
Publicado em: 2009
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2587077/
https://ncbi.nlm.nih.gov/pubmed/18925657
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/syn.20578
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