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Evaluation in Monkey of [(11)C]PipISB and [(18)F]PipISB as Candidate Radioligands for Imaging Brain Cannabinoid Type-1 (CB(1)) Receptors In Vivo
N-(4-Fluorobenzyl)-4-[3-(piperidin-1-yl)indole-1-sulfonyl]benzamide] (PipISB, 3) is a selective and high potency cannabinoid subtype-1 (CB(1)) receptor inverse agonist. We have previously reported radiosyntheses of [(11)C]3 and [(18)F]3. Here we aimed to evaluate the uptake and CB(1) receptor-specif...
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| Main Authors: | , , , , , , , |
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| Format: | Artigo |
| Jezik: | Inglês |
| Izdano: |
2009
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| Teme: | |
| Online dostop: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2587077/ https://ncbi.nlm.nih.gov/pubmed/18925657 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/syn.20578 |
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