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The 2.6 Å Crystal Structure of a Human A(2A) Adenosine Receptor Bound to an Antagonist
The adenosine class of G protein-coupled receptors mediates the important role of extracellular adenosine in many physiological processes and is antagonized by caffeine. We have determined the crystal structure of the human A(2A) adenosine receptor in complex with a high affinity subtype-selective a...
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| Main Authors: | , , , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2008
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2586971/ https://ncbi.nlm.nih.gov/pubmed/18832607 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1126/science.1164772 |
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