The 2.6 Å Crystal Structure of a Human A(2A) Adenosine Receptor Bound to an Antagonist

The adenosine class of G protein-coupled receptors mediates the important role of extracellular adenosine in many physiological processes and is antagonized by caffeine. We have determined the crystal structure of the human A(2A) adenosine receptor in complex with a high affinity subtype-selective a...

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Gorde:
Xehetasun bibliografikoak
Egile Nagusiak: Jaakola, Veli-Pekka, Griffith, Mark T., Hanson, Michael A., Cherezov, Vadim, Chien, Ellen Y.T., Lane, J. Robert, Ijzerman, Adriaan P., Stevens, Raymond C.
Formatua: Artigo
Hizkuntza:Inglês
Argitaratua: 2008
Gaiak:
Article
Sarrera elektronikoa:https://ncbi.nlm.nih.gov/pmc/articles/PMC2586971/
https://ncbi.nlm.nih.gov/pubmed/18832607
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1126/science.1164772
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