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The Roc Domain of Leucine-Rich Repeat Kinase 2 (LRRK2) is Sufficient for Interaction with Microtubules
Mutations in the leucine-rich repeat kinase 2 (LRRK2) gene are the leading cause of genetically inherited Parkinson’s disease (PD). While this multi-domain protein has been shown to have both GTPase and kinase activities through the Roc and MAPKKK domains, respectively, the protein-protein interacti...
Wedi'i Gadw mewn:
| Prif Awduron: | , , , , |
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| Fformat: | Artigo |
| Iaith: | Inglês |
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2008
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| Mynediad Ar-lein: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2586915/ https://ncbi.nlm.nih.gov/pubmed/18214993 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/jnr.21622 |
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