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The Roc Domain of Leucine-Rich Repeat Kinase 2 (LRRK2) is Sufficient for Interaction with Microtubules
Mutations in the leucine-rich repeat kinase 2 (LRRK2) gene are the leading cause of genetically inherited Parkinson’s disease (PD). While this multi-domain protein has been shown to have both GTPase and kinase activities through the Roc and MAPKKK domains, respectively, the protein-protein interacti...
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| Auteurs principaux: | , , , , |
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| Format: | Artigo |
| Langue: | Inglês |
| Publié: |
2008
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| Sujets: | |
| Accès en ligne: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2586915/ https://ncbi.nlm.nih.gov/pubmed/18214993 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/jnr.21622 |
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