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Double-Strand Breaks Induce Homologous Recombinational Repair of Interstrand Cross-Links via Cooperation of MSH2, ERCC1-XPF, REV3, and the Fanconi Anemia Pathway
DNA interstrand cross-linking agents have been widely used in chemotherapeutic treatment of cancer. The majority of interstrand cross-links (ICLs) in mammalian cells are removed via a complex process that involves the formation of double strand breaks at replication forks, incision of the ICL, and s...
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| Main Authors: | , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2007
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2586762/ https://ncbi.nlm.nih.gov/pubmed/17669695 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.dnarep.2007.06.002 |
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