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Differential processing of UV mimetic and interstrand crosslink damage by XPF cell extracts

We have recently developed a mammalian cell free assay in which interstrand crosslinks induce DNA synthesis in both damaged and undamaged plasmids co-incubated in the same extract. We have also shown using hamster mutants that both ERCC1 and XPF are required for the observed incorporation. Here, we...

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Detalhes bibliográficos
Main Authors: Zhang, Nianxiang, Zhang, Xiaoshan, Peterson, Carolyn, Li, Lei, Legerski, Randy
Formato: Artigo
Idioma:Inglês
Publicado em: Oxford University Press 2000
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC115165/
https://ncbi.nlm.nih.gov/pubmed/11095693
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