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hMutSβ Is Required for the Recognition and Uncoupling of Psoralen Interstrand Cross-Links In Vitro

The removal of interstrand cross-links (ICLs) from DNA in higher eucaryotes is not well understood. Here, we show that processing of psoralen ICLs in mammalian cell extracts is dependent upon the mismatch repair complex hMutSβ but is not dependent upon the hMutSα complex or hMlh1. The processing of...

Deskribapen osoa

Gorde:
Xehetasun bibliografikoak
Egile Nagusiak: Zhang, Nianxiang, Lu, Xiaoyan, Zhang, Xiaoshan, Peterson, Carolyn A., Legerski, Randy J.
Formatua: Artigo
Hizkuntza:Inglês
Argitaratua: American Society for Microbiology 2002
Gaiak:
Sarrera elektronikoa:https://ncbi.nlm.nih.gov/pmc/articles/PMC133700/
https://ncbi.nlm.nih.gov/pubmed/11884621
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/MCB.22.7.2388-2397.2002
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