hMutSβ Is Required for the Recognition and Uncoupling of Psoralen Interstrand Cross-Links In Vitro

The removal of interstrand cross-links (ICLs) from DNA in higher eucaryotes is not well understood. Here, we show that processing of psoralen ICLs in mammalian cell extracts is dependent upon the mismatch repair complex hMutSβ but is not dependent upon the hMutSα complex or hMlh1. The processing of...

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Detalhes bibliográficos

Publicado no:	Mol Cell Biol
Principais autores:	Zhang, Nianxiang, Lu, Xiaoyan, Zhang, Xiaoshan, Peterson, Carolyn A., Legerski, Randy J.
Formato:	Artigo
Idioma:	Inglês
Publicado em:	Taylor & Francis 2002
Assuntos:	DNA Dynamics and Chromosome Structure
Acesso em linha:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC133700/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/11884621/ https://ncbi.nlm.nih.govhttps://doi.org/10.1128/MCB.22.7.2388-2397.2002
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