hMutSβ Is Required for the Recognition and Uncoupling of Psoralen Interstrand Cross-Links In Vitro

The removal of interstrand cross-links (ICLs) from DNA in higher eucaryotes is not well understood. Here, we show that processing of psoralen ICLs in mammalian cell extracts is dependent upon the mismatch repair complex hMutSβ but is not dependent upon the hMutSα complex or hMlh1. The processing of...

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書目詳細資料

發表在:	Mol Cell Biol
Principais autores:	Zhang, Nianxiang, Lu, Xiaoyan, Zhang, Xiaoshan, Peterson, Carolyn A., Legerski, Randy J.
格式:	Artigo
語言:	Inglês
出版:	Taylor & Francis 2002
主題:	DNA Dynamics and Chromosome Structure
在線閱讀:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC133700/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/11884621/ https://ncbi.nlm.nih.govhttps://doi.org/10.1128/MCB.22.7.2388-2397.2002
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