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TGF-β subverts the immune system into directly promoting tumor growth through IL-17
Overexpression of the immunosuppressive cytokine TGF-β is one strategy that tumors have evolved to evade effective immunesurveillance. Using transplantable models of breast and colon cancer, we made the unexpected finding that CD8+ cells in tumor-bearing animals can directly promote tumorigenesis, b...
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| 主要な著者: | , , , , , , , , , , , |
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| フォーマット: | Artigo |
| 言語: | Inglês |
| 出版事項: |
2008
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| 主題: | |
| オンライン･アクセス: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2586596/ https://ncbi.nlm.nih.gov/pubmed/18483277 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1158/0008-5472.CAN-08-0206 |
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